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1850
1868 -
The term “stem cell” appears in scientific literature when German biologist Ernst Haeckel used the phrase to describe the fertilized egg that becomes an organism
William Sedgwick uses the term “stem cells” to describe the parts of a plant that grow and regenerate
1886 -
Alexander Maximow presents a theory that all blood cells come from the same ancestor cell
1909 -
1900
1953 -
Leroy Stevens discovered hair, bone, intestinal and blood tissue stem cells
1950
1957 -
E. Donnall Thomas attempts the first human bone marrow transplantation
Ernest McCulloch and James Till perform experiments on the bone marrow of mice - blood stem cells
1963 -
Robert A. Good performs the first successful bone marrow transplant on a child patient
1968 -
1981 -
Martin Evans and Gail Martin conducted separate studies and derive pluripotent stem cells from the embryos of mice​
1986 -
Andrew Lassar and Harold Weintraub converted rodent fibroblasts (connective tissue) into myoblasts using a single gene
Mario Capecchi, Martin Evans and Oliver Smithies created the first “knockout mice”, which were missing specific genes
1989 -
Dominique Bonnet and John Dick discover that leukemia comes from the same stem cells that make our blood cells
1997 -
1998 -
James Thomson and Jeffrey Jones reported the creation of the first batch of human embryonic stem cells
2000
2002 -
George Q. Daley reports combining the use of gene and cell-based therapy to treat a mouse model of immune deficiency
Woo-Suk Hwang used therapeutic cloning to create 11 stem cell lines that match their donors
2005 -
Shinya Yamanaka and Kazutoshi Takahashi announce the creation of rodent induced pluripotent cells (iPS cells)
2006 -
2006 -
George Q. Daley reports the creation of donor-matchedembryonic stem cells in mice through parthenogenesis
2007 -
 Shinya Yamanaka, James Thomson, and George Q. Daley announce that they have created human iPS cells (unrelated)
The Stem Cell Program at Boston Children’s Hospital announces the creation of 10 disease-specific lines of iPS cells
2008 -
Barack Obama signs an Executive Order to repeal some restrictions on human embryonic stem cell research funds
2009 -
2010 -
First experiments using embryonic stem cells on humans suffering from spinal cord injury and blindness begin
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"Now science has presented us with a hope called stem cell research, which may provide our scientists with many answers that have for so long been beyond our grasp"

- Nancy Reagan

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